- Image via Wikipedia
I was adopted and later in life searched for my biological parents, who I eventually found. To my utter surprise, I found that my biological mother and father had had a “love fling” and I was the product of that, which occurred before they were married – forcing them to have me in secret and give me away. The really amazing part is they ended up getting married and having two more children, giving me a full biological brother and sister. A reunion with all but my bio-father, who had passed away, has led to some wonderful relationships. But even cooler is the fact that each of them has genetically got some of the same mood disorder problems I have. Due to my sister finding out she has a propensity toward depression — such as I had and beat with a lot of medical trial and error, it allowed me to write her the following letter of advice, which I’d say could DEFINITELY apply to ANYBODY who is fighting depression. Please read on to see what I wrote her about my amazing comeback. I’ll call her Heidi for her privacy:
After speaking of a long period of very high productivity I said to Heidi, who had been turned down for a miracle drug called Deplin by her shrink: “Never in a million years could I be so productive without feeling great. To answer your question, Deplin is one of 3 drugs I take for my moods. I take something called Pristiq — which is the latest generation of Effexor — and I absolutely love it. It is an antidepressant just like your Zoloft but it has a better effect on anxiety, for me, anyhow. I’m also on a small dose of a mood stabilizer to keep me from taking dives called Trileptal. I don’t know how effective it is but I’m not messing with my cocktail because it works. Then there is the Deplin, which in my opinion got everything working — because before the Deplin it was like — Doc, what the hell? And I am on the LOW dose as it comes in 7.5mg (mine) and 15 mg. I just didn’t feel that bubbly sense of myself that I knew was in there. When I went on that stuff, Heidi, it was like my icing on the cake, mood-wise.
You know, some doctors just never adventure outside their little box of familiarity, and after witnessing hundreds of people being treated when I ran those sober livings, I could tell who was being treated effectively, and who wasn’t. I don’t want to stick my nose too far into your business, but you need to remember that the doctor is working for YOU. I would make sure you made the effort to go to town and say “listen, my biological brother and I both have a very similar problem with depression, and he was on anti-depressants and mood stabilizers, and he didn’t feel like they were totally effective until they added Deplin to the mix. As I understand it, Deplin is simply a prescription vitamin of sorts, that absolutely facilitates the manufacture of serotonin and dopamine AND nor-epinephrine. And that’s what we are trying to do, is get my levels of serotonin and dopamine and nor-epinephrine up– so I don’t understand why or how it couldn’t be a good idea for me to at least try it. I mean, I have close to a biological twin out there and it works for him.. that should mean something, don’t you think, given that Deplin corrects a genetic defect?”
If you let him/her know about the biological link, the therapist should jump on the idea because the biggest thing about the shortage of L methylfolate in the brain is – IT’s GENETIC!! It’s true — we likely have the same damn bugs in our brains Heidi, why not help each other find the cure? I’d be very curious after that if this person says no, what their reasoning is — because Deplin’s ingredients reverse a deficit in folic acid and folate that depressed people are lacking over 70% of the time — women more than men- , ie the Vitamin B metabolic effect — and you can’t get nearly, I mean NEARLY the same levels no matter how many supplements you take. Maybe there is something about Deplin I don’t know, but I have researched it pretty thoroughly. Sometimes you need to really ring their bells, Heidi, like say — “I don’t know if you are hearing me. I really want to add Deplin to my therapy”. Go here and print this out. It has all the studies and tells you in a NUTSHELL why you should benefit so greatly from this: 7 out of 10 people with depression may have a specific genetic factor that limits their ability to convert folic acid or folate from the diet to L-methylfolate.11 This is important because L-methylfolate is the ONLY form of folate used by the brain to correct a neurotransmitter imbalance linked to depression.
And, my sweetheart, I can obviously not guarantee that it is any magic bullet for you– I just know that from all I have read I can’t see how it can hurt, and there is a great chance it can help. It takes 2-4 weeks to start working, so don’t expect any instant miracles, but if it works for you like it did me, one day you’ll just find you feel more like yourself, and that’s a huge thing in my book. When you are depressed life is just wasting away, because you are so damned busy fighting the depression. You have to MAKE yourself get up and go do this or go do that — and you really don’t want to do those things, and you likely don’t enjoy them when you do! You’d rather just hunker down in your hole, right? Where you are more comfortable. At least that’s the way it was for me.
Now that I am better, I am adamant about pushing other people to go about getting better as best they can — because it is so not worth feeling down. And only those people who have BEEN truly depressed can honestly describe it, and understand how utter and total the feeling is. The shame of it is you care so little about stuff, that you don’t really care about yourself.
I’ll add one more thing because I care so much about you, then I’ll shut up. I learned in all my research about a condition called Dysthymia. Dysthymia is interesting because it is not characterized as full blown depression. Moreover, it is defined as a low-grade depression that persists for years– it’s just constant — never letting up. Dysthymia, if not treated, almost turns into depression 100% of the time, but I am bringing it up with you because I wonder if I wasn’t Dysthymic alot of the time –where I wasn’t totally depressed, but where if you described normal life as full of exciting colors, I saw everything in shades of grey alot of the time (whereas fully depressed everything is just black). So don’t rule out that you could be Dysthemic, too — which is treated exactly like depression — I mean with the same drugs. Go here to check it out https://health.google.com/health/ref/Dysthymia
So, my dear, I say all this because I just want you to feel better, and I think we are alot alike insofar as how prone to depression or being blue that we are. So start with getting that therapist to allow you to try Deplin — because talk therapy is truly great, but you and I need our chemicals balanced to feel really right. And I remain a strong proponent of the Deplin so don’t let it slide. And if the answer is no, push it, ie ask what’s the harm? And whatever it is, if it doesn’t sound 100%, say that’s a risk I am prepared to take (unless there is some cross-effect with another medication you are taking or something I don’t know about!) I might talk like one, but I know I’m not a doctor. But I do love you and just want you feeling your best because you deserve it. xoxoxoxoxoxox me
PS: READ THE SITE ABOUT DEPLIN ABOVE AND WHILE I AM NOT PARANOID, I WONDER IF SOME OF THESE SHRINKS DON’T WORRY ABOUT LOSING PATIENTS IT WORKS SO WELL!
Related articles by Zemanta
- Supplements for depression: What works, what doesn’t (cnn.com)
- What are the Symptoms of Dysthymia? (brighthub.com)


